New article published in Frontiers of Immunology in the section of Alloimmunity and Transplantation

October 14, 2025

"Clinical management and burden of cytomegalovirus in D+/R-Kidney transplant recipients in Canada" was published in the section of Alloimmunity and Transplantation of Frontiers in Immunology.

Purpose: To document prophylactic practices, infection patterns, and disease burden to inform strategies for CMV management in high-risk kidney transplant recipients.

Conclusion: Current prophylaxis strategies fail to prevent CMV infection in 34% of high-risk patients. Myelotoxicity, opportunistic infection, reduced immunosuppression, and hospitalization remain common and serious complications. More effective and less toxic personalized treatment strategies are required to minimize these risks and burdens.

Read the full article here


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